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Photo: Etan J. Tal, CC BY 3.0 via Wikimedia Commons
The Wise Observatory, far enough from the town to avoid light pollution, is remotely-operated by the Tel Aviv University. The facility is unmanned so really there isn't much to see or do, except watch the structure from the outside.
The Florence and George Wise Observatory is an astronomical observatory owned and operated by Tel Aviv University. It is located 5 kilometers west of the town of Mitzpe Ramon in the Negev desert near the edge of the Ramon Crater, and it is the only professional astronomical observatory in Israel.
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The largest of its kind outside of South America, the farm houses llamas and alpacas the visitors can pet and even ride. The farm also offers bed & breakfast rooms, contains a souvenir shop selling alpaca-related products, and conducts paid tours riding alpaca.
Sunset Point
Great for sunset if you, for example, stay in The Green Backpackers. Best time is 17:30 in March (Golden Hour).
A museum showcasing the wildlife of the desert and the crater. The rich collection of desert plants and animals displayed is divided into two parts: an indoor interpretation center and an outdoor area reconstructing the Negev desert landscape, with desert loess, hamada, sand, cliffs, riverbeds and even a small spring.
A trail decorated with impressive environmental sculptures, starting from the Visitor Center and going along the edge of the crater. In its middle is a "bird balcony" which hangs over the crater and offers the best view around. The paved trail is fairly accessible for the disabled, and beyond it a dirt path goes on along the edge to Har Gamal (Mount Camel) – a small observation platform atop a rock resembling a camel.
Renovated in memory of the first Israeli astronaut, whose surname happened to be Ramon, visitors to the center walk through several exhibition rooms. The first ones are dedicated to the memory of Illan Ramon and the crew of space shuttle Columbia, as well as to Ramon's son, Asaf, who died as a military pilot in a training accident. The following rooms are dedicated to the crater – its geology, wildlife and history – and contains an impressive 3D exhibition, showing very clearly the process by which the crater formed.
A performance house with a pretty busy schedule. Unfortunately their website is only in Hebrew (although Google will translate the page), but you can try contacting them and ask about upcoming performances, or simply show up and enjoy whatever you get.