Photo: Hubert Berberich (HubiB), CC BY 3.0 via Wikimedia Commons
The original Steinmeyer Organ with about 8000 pipes is one of the biggest within Germany and was built in 1911.
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m:con
Music concerts and conferences.
Wasserturm
One of the most famous icons of the Jugendstil (Arte-Nouveau style) in Germany, the water tower (and small park surrounding it) is a great place to sit in the summer for a picnic or just a little rest (officially, walking or sitting on the lawn is prohibited). The park is surrounded by the Rosengarten, a conference hall of reddish brick, and the colors on a sunny day are amazing.
NTM
One of the most important theatres in Germany. "The Robbers" by Schiller had its world premiere here. Has a different show almost every night (for some shows, like ballets or opera, the language barrier is not an issue).
Art Gallery
A museum for modern and contemporary art featuring an extensive collection of sculptures and paintings from the 19th century to the present. The facility consists of a historic building from 1907 and a modern extension, housing both permanent galleries and temporary exhibitions.