Santo Domingo was the first major European settlement in the New World. Christopher Columbus walked these streets! Check out the many examples of 15th and 16th century architecture in the Colonial Zone. Don't miss the Ozama Fort (built within Columbus's lifetime), the Alcazar de Colon, and the Cathedral, all dating to the early 1500s. You can also check beautiful churches and convents, such as the Iglesia Regina Angelorum and the Convento de los Dominicos. Don't miss the Panteon Nacional, where the national heroes are buried, in the Calle Las Damas, the New World's first (European) street! Also, walk up the Calle del Conde, a very old pedestrian shop-lined street that used to be the commercial heart of the city. This street leads to the Puerta del Conde, where the Dominican Republic proclaimed its independence from Haiti, and the Parque Independencia, where the country's founding fathers' remains are kept at the Altar de la Patria. On Sunday evenings, check out the Ruinas de San Francisco for live bands playing Merengue, Bachata, Salsa and Son, in a wonderful weekly show where both locals and tourists dance, drink and enjoy themselves. This would be an unforgettable experience! Also check out La Atarazana street after dark for a variety of romantic outdoor cafes with a spectacular view of the Alcazar and bay area. One such brasserie, Pat E Palo, has operated uninterrupted since 1505. Check out the house where Ponce DeLeon lived before he embarked upon his quest for the fountain of youth and ended up discovering Florida.
An important landmark because it is the first cathedral of the Americas. Construction began in 1514, and was finished in 1540.
Ozama Fortress
The oldest formal military construction still standing in the Americas. Cost of entrance is RD$200 per person and about RD$200 for a guide to take you. The guide is recommended because he will explain much of the historical background. The fortress itself is not very large, but within the perimeter you will find a large open area with a park and an exhibition of military vehicles and weapons, most of them relatively modern.
Head of state location for the Dominican Republic. No entry, but the structure is very grandiose and warm-feeling with its orange hue.
Museo Alcázar de Colón
Visit this stunning villa, built in 1510 and retaining period furnishings and other items owned by Governor Diego Colón, first-born son of Christopher Columbus. As of March 2025, it's undergoing renovations.
Museo Naval de las Atarazanas
Located across the plaza from the Alcazar de Colon on Calle Atarazana, the oldest street in the Western Hemisphere.
Museo de las Casas Reales
Another great museum featuring collections depicting life in 16th-century Santo Domingo. It is walking distance from the Alcazar de Colon and the Naval Museum. In September 2025, under renovation