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Visit this stunning villa, built in 1510 and retaining period furnishings and other items owned by Governor Diego Colón, first-born son of Christopher Columbus. As of March 2025, it's undergoing renovations.
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Museo del Ron Dominicano
This museum holds all the history of rum making in Dominican Republic. In the front of the museum you will find all the Dominican rum for sale at reasonable prices. There is also a very nice bar inside where you can enjoy a nice drink of rum or any other drink you like. In the after hours it turns into a bar (read below).
Might be kind of cheesy, but it's almost like a living history museum of the DR's past. A collection of artifacts and writings regarding the Dominican Republic's founding father, Juan Pablo Duarte.
An impressive collection of amber stones.
Museo Naval de las Atarazanas
Located across the plaza from the Alcazar de Colon on Calle Atarazana, the oldest street in the Western Hemisphere.
Museo de las Casas Reales
Another great museum featuring collections depicting life in 16th-century Santo Domingo. It is walking distance from the Alcazar de Colon and the Naval Museum. In September 2025, under renovation
If you want to try making chocolate or bar soap, this is a place for that, in addition to tours of a confectionary and buying sweet stuff.