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In this park, you'll find a microcosm of local history in the form of the Templo y Convento San Francisco, Franciscan in nature c. 1688; the Museo Histórico Provincial de Santa Fe; and the Ethnographic Museum Colonial Juan de Garay, with excavated findings from the original Santa Fe settlement, among other things. You can also potentially see some exhibits about Pope Francis at the Colegio de la Inmaculada Concepción next door, where he went to school from 1964-1965.
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House museum of a former Argentinian brigadier general.
Here is a place to see some various works of art.
Natural history museum; great if you are wanting to see loads of taxidermy on display, but a very detailed coverage on the subject nonetheless.
A place where you can throw some money away.
Describes the story of the formation of the Argentinian Constitution that consummated here, in an interactive way, with some nice emblematic sculpture along the riverfront outside.
This location offers short boat ride tours enabling you to appreciate Santa Fe from the water as well as Laguna Setabal itself. Contact info is a little lacking.