Photo: w_lemay, CC BY-SA 2.0 via Wikimedia Commons
Designed by Louis Sullivan and built in 1890, it is one of the world's first skyscrapers. Its current occupant is the Missouri Secretary of State.
The Wainwright Building is a 10-story, 135-foot (41 m) terra cotta office building at 709 Chestnut Street in Downtown St. Louis, Missouri. The Wainwright Building is considered to be one of the first aesthetically fully expressed early skyscrapers. It was designed by Dankmar Adler and Louis Sullivan and built between 1890 and 1891. It was named for local brewer, building contractor, and financier Ellis Wainwright.
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Citygarden gives kids fountains to play in and sculptures they can related to (Pinocchio, big heads, etc.); art lovers the chance to experience 24 sculptures by some of modern art's great masters (Leger, Herring, etc.); and everyone an award-winning garden in the midst of the city where you can relax and beat the heat. If you'd like to eat in the gardens, there is a cafe that is open for lunch or you can pick up something from the many takeout places nearby.
The site of the historic Dred Scott slavery case which was one of the seeds of the Civil War. While the Park is under construction, you can buy tickets to the arch here. The Courthouse also holds exhibits from the now-closed Museum of Westward Expansion, which used to be underneath the Arch.
MLB
St. Louis' Major League Baseball team (and the 2011 World Series champions) has won 11 World Series titles, the most of any National League team, and second only to the New York Yankees. The Cardinals play in the Central Division of the National League. Behind-the-scenes tours of the ballpark are available daily all year (except for days with an afternoon home game) at 11AM and 12:30PM.
Basilica of Saint Louis, King of France
The first cathedral built west of the Mississippi River (1834), this is the only building that was spared when the park was constructed. It's still an active Roman Catholic basilica.
Over 500,000 square feet of exhibit space, also featuring formal reception rooms, presentation-style rooms, a theatre, and the Edward Jones Dome next door.
A large park with plenty of big lawns, wooded areas, and a few ponds. The park and the nearby parking garage are closed for renovation; however, the arch remains open.