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Don't forget to go and see the real fishing boats at what's known as Fish Alley — after all it is "Fisherman's Wharf". If you want to see them actually hauling in their catch, you'll have to be there around 6AM to 7AM.
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Built in 1907 with its award-winning architecture, the Cannery overlooks San Francisco Bay and once upon a time was the largest peach cannery in the world. Today it's a bustling marketplace featuring three levels of restaurants, shops, offices, and live entertainment. In the middle it has a secluded courtyard with outdoor bars and cafes.
The Visitor Center has an information desk and a bunch of small craft and hands-on exhibits that depict San Francisco's rich maritime heritage, with a special focus on the region's economic history. It provides some information about the boats that line Hyde St Pier.
This tiny chapel is a memorial to the "Lost Fishermen"... those that have lost their lives on the seas. Different religions are represented with separate altars on different sides of the tiny chapel. Every year they hold a special service to commemorate these fishermen. The annual "Blessing of the Fleet" also starts from here every October.
A museum all about the eye: anatomy, vision, eye disorders and treatment, the history of ophthalmology, and rotating exhibitions. Run by the American Academy of Ophthalmology, it's well worth a visit if you're in the area and at all curious to learn about how eyes work.
An fun exhibit that traces the history of amusement attractions in American cities, with a focus on San Francisco.
Probably the largest and most extensive antique arcade in the world. Several hundred coin-operated musical instruments, antique arcade games, fortune telling machines, and mechanical dioramas. that date from the turn of the century to the early 1990s. The proprietor is typically moving around the space on rollerskates, doing maintenance on the machines.