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Rent a bike and explore the many remains of the Appian Way park area.
Porta San Sebastiano is a gate in the amazingly well-preserved Aurelian Walls. Inside and upstairs is a museum dedicated to the construction of the walls and their recent restoration. You can take a walk along the top of the walls. At the museum you can also arrange to visit the Tomb of the Scipios (Sepolcro degli Scipiani) and a nearby Roman Columbarium (tomb for cremated remains), the entrance for which is 200 m back towards Rome along the Via Di Porta San Sebastiano. No wheelchair access.
This is not the real name of the church on the corner by the main entrance to San Callisto but it is universally known by this name. By legend it is located on the spot where Saint Peter had a vision of the risen Christ while fleeing persecution in Rome. According to the tradition, Peter asked Jesus, Domine, quo vadis? “Lord, where are you going?” The current church is from 1637. Inside is a copy of a stone said to contain the imprints of the feet of Jesus; the original is maintained in San Sebastiano, further along the Appian Way
A 1st-century tomb surrounded by two farmhouses from the Middle Ages, one of which used to be a cheese store. Rather hidden behind a high wall, the tomb is rarely open to the public. You might be lucky on a Sunday: on the third Sunday of every month there is a guided tour at 11:00.
Although started in the 2nd century, San Callisto has had many more recent burials, including 16 popes. The burial arcades are almost 20 km long.
The Catacombs of Domitilla are considered to be the best preserved of all Roman catacombs. They are the only ones still to contain bones. Domitilla also has a subterranean basilica, much of which was reconstructed in 1870.
The first basilica was constructed in the 4th century and dedicated to San Sebastian, a martyr of the 3rd century. Sebastian's remains were transferred to St. Peter's in 826, prior to a Saracen assault when the church was destroyed. The current church was largely constructed in the 17th-century. Until the Great Jubilee in 2000 this was one of the Seven Pilgrim Churches of Rome, i.e. the churches that all Roman Catholic pilgrims were expected to visit. However, at that time it was replaced by the Sanctuary of Divino Amore (see below). Entrance to the catacombs, which are smaller than the others in the area, is to the right of the church entrance. The area where you buy tickets and wait for tours has a good display of sarcophagi from the catacombs. You can rent a bicycle at the catacombs for further exploration of the Appian Way.