In case you are into Catholic churches dealing with the Guadalupe theme.
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This old locomotive workshop building in the shape of a rotunda has some architectural flair.
Some fun hiking paths here in the bottomlands of the Rio Santa Fe.
It's like the closest thing to a beach in these parts, and it's along the Rio Santa Fe. But don't let it sound disappointing, as the sand is decent and it has Santa Fe's impressive suspension bridge in the foreground.
Possibly the landmark that most defines Santa Fe aside from the river, this suspension bridge can be fun to walk or drive over. Also, on the western embankment sits the Brigadier Estanislao López Monument, with the general on horseback, along with a long river walk, the Costanera Santa Fe.
This could be a fun little plaza just for experiencing daily Argentinian life in this city. Plus it is well visited and safer than some of the other outdoor locations.
This location offers short boat ride tours enabling you to appreciate Santa Fe from the water as well as Laguna Setabal itself. Contact info is a little lacking.